Iris Publishers-Archives in Biomedical Engineering & Biotechnology | Atypical Ductal Lesion in the Breast
Authored by Shinya Tajima
Atypical ductal lesions of the breast are considered mainly “Atypical ductal hyperplasia (ADH)” ADH is defined as intraductal feature of architectural atypia [1]. However, diagnosis of ADH is challenging, because the interpretation of diagnosing ADH is different and vary between diagnostic pathologists. Goi S [2] advocated two pattern theory in the breast [2]. First, true borderline malignancy lesions are existed in the breast. Second, true borderline malignancy lesions are not existed, because borderline malignancy lesions which was thought at a glance are not true borderline lesions but pathologists cannot divide between malignant and benign because of their incapable. Goi S. thought that the latter theory was appropriate. Furthermore, he also thought that benign and malignant should be rigidly separated, and the most important thing is to reduce over diagnosis or under diagnosis. However, our recent study indicates the existence of the true borderline lesion. After paragraph, I will write this matter in detail. In addition, ADH is not clearly understood whether borderline malignancy or not, and that is still wrapped mysteriously. In this paragraph, we will depict about the characteristics of ADH. The definitions of ADH are clonal intraductal proliferation with architectural and cytologic features approaching those seen in low-grade ductal carcinoma in situ.
To read more... Biomedical Engineering and Biotechnology
To view more Journals... Iris Publishers
Atypical ductal lesions of the breast are considered mainly “Atypical ductal hyperplasia (ADH)” ADH is defined as intraductal feature of architectural atypia [1]. However, diagnosis of ADH is challenging, because the interpretation of diagnosing ADH is different and vary between diagnostic pathologists. Goi S [2] advocated two pattern theory in the breast [2]. First, true borderline malignancy lesions are existed in the breast. Second, true borderline malignancy lesions are not existed, because borderline malignancy lesions which was thought at a glance are not true borderline lesions but pathologists cannot divide between malignant and benign because of their incapable. Goi S. thought that the latter theory was appropriate. Furthermore, he also thought that benign and malignant should be rigidly separated, and the most important thing is to reduce over diagnosis or under diagnosis. However, our recent study indicates the existence of the true borderline lesion. After paragraph, I will write this matter in detail. In addition, ADH is not clearly understood whether borderline malignancy or not, and that is still wrapped mysteriously. In this paragraph, we will depict about the characteristics of ADH. The definitions of ADH are clonal intraductal proliferation with architectural and cytologic features approaching those seen in low-grade ductal carcinoma in situ.
To read more... Biomedical Engineering and Biotechnology
To view more Journals... Iris Publishers
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