Association Between the Salivary Streptococcus Mutans Levels and Dental Caries Experience in Adult Females - Dentistry & Oral Health

 

Streptococcus mutans has been concerned like one of the main etiology  of  dental  caries  [1,2].  It  is  known  that  tooth  surfaces  inhabited with S. mutans are on a high risk of developing caries [1-3].  Appearing  in  people  with  a  relatively  high  caries  experience,  a  positive relationship between high salivary levels of Streptococcus mutans and  dental  caries  experience  have  been  reported  [4,5].  Those with high levels of Streptococcus mutans as well acquire more coronal  and  root  caries  in  permanent  restorations  and  temporary  restorations  than  persons  appearing  in  the  same  population  with  lower  intensity  of  Streptococcus  mutans [5-7].  S.  mutans salivary  levels are straight linked to the number of tooth sites colonized [8] and to their amount in dental plaque [9]. 

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Macular Changes after Uneventful Phacoemulsification in Diabetic Patients in a Tertiary Hospital - Ophthalmology & Vision Research

The  incidence  of  subclinical  macular  edema  after  uneventful  phacoemulsification  has  become  an  issue  of  safety  for  this frequently performed operation. Advances in phacoemulsification techniques   and   intraocular   lens   design   have   led   to   improved   outcomes following cataract surgery. Nevertheless, ME may develop and can result in suboptimal postoperative vision [1].

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Pericardial Synovial Sarcoma: A Case Report and Review of Literature - Cancer Research & Clinical Imaging

Pericardial Synovial Sarcoma (PSS) is a rare malignant soft-tissue tumor. Early diagnosis and multimodal management could be improving patient outcome. PSS diagnose is difficult due to localization but and aggressive disease. Using all the available medical methods is important to avoid progression and recurrence of this kind of tumors. Multidisciplinary treatment is necessary and radiotherapy is a good and safe option. We present our experience of a forty-year-old man with this tumor.

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Solutions of Formaldehyde in Water and Alcohols - Pharmacy & Pharmacology Research

A mechanism of the initiated nonbranched-chain process of forming 1,2-alkanediols and carbonyl  compounds  in  alcohol– formaldehyde  systems  is  suggested.  The  quasi-steady-state  treatment  is  used to obtain kinetic equations that can describe the nonmonotonic (with a  maximum) dependences  of  the formation  rates of the product on the concentration of free unsolvated  formaldehyde. The experimental concentrations of the free unsolvated form of formaldehyde are given at the different temperatures, solvent permittivity, and total concentrations of formaldehyde in water and alcohols. An empirical equation for calculating the free formaldehyde concentration in alcohol–formaldehyde (including water/ethanediol–formaldehyde) systems at various temperatures and total formaldehyde concentrations and an equation for evaluating solvent concentrations in these systems were derived.

 

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The Future of Health and Healthcare in a World of Artificial Intelligence - Biomedical Engineering & Biotechnology

 

Artificial Intelligence (AI) consists a set of computational technologies that designed to sense, learn, reason, and take action. AI  has  already been integrated in  many  applications including  automating  the  business  processes,  gaining  insight  through  data  analysis, and  engaging  with  customers  and  employees. AI  enabled  machines using  deep learning  algorithms  has  been  shown  to  exceed human performance, particularly in visual tasks like playing Atari games, strategic board games like Go and object recognition etc. Furthermore, with the technological advancement in mobile computing, artificial neural networks, robotics, storage of huge data in internet, cloud-based machine learning and information processing algorithms etc. application of AI has been integrated in many sectors including transportation, service robots, health care, education, low-resource communities, public safety and security, employment and workplace, and entertainment etc. In this review, we have highlighted the recent trends and applications of AI in healthcare  i.e. mining  medical records (EHR), designing treatment plans, robotics mediated surgeries, medical  management  and  supporting hospital operations etc. There are many AI platform has been designed which has also been proved to be instrumental in the development of innovative drugs. There is no doubt that AI will enhance the cooperation between humans and machines in years to come and will play an integral role in the improvement of the health index and quality of life. 

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Investigation of Shock-Boundary Layer Interaction in a Ramp Flow with MVG Under Different Turbulent Inflows - Engineering Sciences

MVG (micro vortex generator) is a potentially new device which can alleviate or overcome the adverse effects of SBLI (Shock-boundary layer interaction) and improve the “health” of the boundary layer. In this paper, the SBLI in a ramp flow with MVG under different inflow conditions is investigated by LES (large eddy simulation). Three turbulent inflows with different boundary layer

thickness are generated based on turbulent profiles obtained from DNS (Direct numerical simulation) of transition. The numerical results show that the interaction between ring-like vortices generated by MVG and the ramp shock is influenced by these different inflow conditions. With lower boundary layer thickness, the ring-like vortices are less distorted and thus more stronger when they travel to the ramp corner. The more regular and stronger ring-like vortices have more capability to eliminate or distort the strong ramp shock wave. Moreover, it confirms that ring-like vortices generated by MVG, and not the lower turbulent boundary layer, is dominant in flow separation reduction.

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Numerical Simulation of Phase Transformation and Reorientation in Single Crystalline Shape Memory Alloys - Engineering Sciences

In our previous paper [1],  a constitutive  model  was  developed  for  the  stress-induced  martensitic  transformation  and  reorientation in single crystalline shape memory alloys. The critical condition and evolution equation for the phase transformation and reorientation were proposed. In this paper, the model proposed in our previous paper [1] is applied to simulate the behavior of stress-induced phase transformation in a CuZnAl single crystal and reorientation between CuAlNi martensite lattice correspondence variants. It is found out that the prediction results are consistent with the experimental data reported in the literature.

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Initial Yield Surface of Shape Memory Alloy in Stress Induced Martensitic Phase Transformation- Engineering Sciences

Based on the critical conditions for nucleation and the actual eigenstrain of a given shape memory alloy in the stress induced martensitic phase transformation, the closed-form expression of its corresponding initial yield (nucleation) surface is obtained. Consequently, the underline mechanism for non-symmetry in the stress vs. strain relationshipbetween uniaxial tension and uniaxial compression experimentally observed in many SMAs is revealed. Unlike that in many traditional criteria, such as the Von Mises and Tresca criteria, in which the yield surfaces are functions of stress only, the yield surface derived here is closely related to the crystal structures before and after the phase transformation. The initial yield surface of a polycrystalline CuZnAl shape memory alloy tube
under combined loading of tension and torsion predicted by the formula developed here agrees well with the experimental results reported in the literature.

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Foreign Body in Thigh of Crawled Baby: Case Report - Clinical Case Studies

 

Before  age  of  6  months  foreign  body  injuries  by  penetrating  bodies  are  very  rare  and  extraordinary  form  of  childhood  injuries  [1].  When  we  examine  the  literature,  it  is  suggested  that  the  childhood  penetrating  body  injuries  particularly  occurred  by  the  sewing needles should be considered as non-accidental injuries and especially  child  abuse  should  be  kept  in  mind.  It  is  suggested  that  the  pediatrician  or  the  emergency  doctors  who  initially  examine  these patient must be careful [2]. Diagnosis needs multidisciplinary approach  [3].  Some  other  findings  in  the  examination  should also be searched to suspect child abuse. These findings can be multiple bruises in different healing age, bone fractures on atypical localizations, burns and there is usually a delay in presentation [4]. In our case interestingly there are not any additional examination findings or pathology to suspect child abuse and it is excluded by family examination and the history of event.

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Stable Isotope Analysis of C,H,O and N in Finger Nails from Different Areas in China - Forensic Science & Medicine 

In recent years, stable isotope analysis has become an important method in forensic science. This method is used to investigate still unresolved criminal cases and to discover the geographic origin or place of residence of unidentifiable deceased people. In order to explore isotopic characteristics in human tissues from different areas in China, four isotope compositions (δ13C, δ15N, δD and δ18O) of fingernails from 24 individuals lived in two different cities, Xuanhan and Xianyang, the south and north of Qinling Mountains, were analyzed. The values of δ13C, δ15N, δDand δ18O in fingernails have significant difference between the two cities(p<0.05). From the figures of δ13C against δ15N, or δD against δ18O, it is easy to identify an individual is from Xuanhan or Xianyang. The δD and δ18O values of drinking water were also significantly correlated with those of fingernails (Pearson coefficient was 0.926), indicating that it is possible to deduce the δD and δ18O ratios of fingernails from those of drinking water. A larger database on multi-element isotope value of human tissue, such as fingernails, hair, bone, and so on, from different areas of China is being established. It will become a more powerful tool to answer the questions regarding the provenance of unidentified corpses, major geographic movement in the lifetime and dietary habits of an individual involved in murder case and be useful for exploring more information in various serious cases in the future.

 

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Non-Convulsive Status Epilepticus in Ischemic Stroke and its Impact on Prognosis - Neurology & Neuroscience

Non-convulsive    Status    Epilepticus    (NCSE)    is    an    under    reported,  treatable  cause  of  coma  and  has  variety  of  clinical  and  EEG presentations. It is defined as a mental status with changes from base line of at least 30 - 60 minutes duration associated with continuous or near continuous ictal discharges on EEG [1]. 

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Population Projection and Adjustment Methodologies for Household Sample Surveys: an Overview of Methodology - Biostatistics & Biometric Applications

Population projections are essential for updating the population information which will be used as the ideal sampling frame for many surveys such as health, agriculture and many others. The techniques used to make population projections can be classified as mathematical models and cohort component projection models. Mathematical models are useful when we only need to project the total and domain populations. Therefore, they use total population figures from the past to project future population levels. Among the possible alternative curve fitting methods like linear, geometric, logistic and exponential, the most widely used mathematical model for population projections is exponential model.

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Client Assessment and Formulation with Person Centered Approach - Neurology

The case study of this paper is about Laura, 51yrs old lady, who has  faced  personal  upheaval  for  which  she  is  experiencing  severe  trauma. Laura had a head injury 10 years ago that led to her cognitive difficulties  charac-terized  by  executive  dysfunction  including repetition, impulsiveness, poor planning, and disinhibition.

 

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Alcohol in Mexico: Dying, Like Sucking, also is Gerundio - Addiction and Psychology

Alcoholism  is  by  far  the  addiction with  the  highest  prevalence  and  incidence  in  our  country;  only in  2011  were  detected  around  six  million  people  with  a  harmful consumption  of  alcohol,  and  that  they  developed  some  of  the  52  diverse conditions already described. And  it  is  not  only  the  liver,  with  its  sequence  of  intoxication, congestion, hepatic steatosis  (some  call  it  fatty  liver), hepatitis, cirrhosis   and   some   even   liver   cancer;   we   also   have   alcoholic   pancreatitis, heart disease (alcoholic   cardiomyopathy), mental problems such as Wernicke’s  disease  or Korsakoff ’s  psychosis.

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Occurrence of Mature Female of Etmopterus Spinax (Chondrichthyes: Etmopteridae) in the Syrian Coast (Eastern Mediterranean) - Oceanography & Marine Biology

 Velvet Belly Lantern shark, Etmopterus spinax (Linnaeus, 1758) is recorded for second time in the Syrian coast. A mature female of E. spinax measured 354mm total length, and weighed 208.3g, caught at depth about 300m. the specimen was in stage 3, had two ovaries; contained 9 oocytes measured between 10-5mm in diameter. The width of left and right oviducal gland measured; 8mm and 7mm, respectively. It had left and right functional uterus, white color measured; 77mm and 75mm in length; 11mm and 10 mm in width, respectively.

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Prenatal Diagnosis of Heart Rabdomioma. A Case Report - Gynecology & Womens Health 

We describe a case of a heart tumor diagnosed by ultrasound in a 20 week’s gestational age fetus with presumptive diagnosis of heart rabdomioma. The fetus was delivered by cesarean section because a previous section at 38 weeks of gestational age. At the evaluation of the new born, the diagnosis of rabdomioma was confirmed by echocardiogram. We report of a case of prenatal rabdomioma associated to maternal diagnosis of tuberous sclerosis.

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The Effectiveness of Attentional Training on Stress and Self-Esteem - ANN

Stress has been an immeasurably investigated theme within Neuropsychology since past few years. Attention training is a therapeutic intervention developed by Adrian Wells that involves the training of attentional skills to treat emotional disorders (Wells, 1990). This study investigated whether the Attentional training works as theorised to reduce stress. In addition, self-esteem and stress were investigated as potential moderators of the relationship between Attentional training and/or self-focus on vulnerability to the stressor. Prior research has shown that self-esteem level and self-focus interact such that self-focus predicts vulnerability to stress in people with low self-esteem, but not in those with high self-esteem. In a laboratory setting, 80 undergraduate student participants were exposed to a single session of either an Attention training analogue or a control treatment to see if Attentional training would reduce their stress to a subsequent stressor task.

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Rett Syndrome: Reporting A Case and Review in Literature - ANN

Rett syndrome is a disorder in children’s neurological development characterized by an initial normal evolution followed by the loss of voluntary use and characteristic movements of the hands, a delayed growth of the brain and head, difficulty walking, seizures and mental retardation. The syndrome affects almost exclusively girls and was identified by Dr. Andreas Rett in 1966.

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Mioclonic Epilepsy with Red Ribbed Fibers (Merrf ): Report of a Case and Review in Literature - ANN

MERRF is a multiple system disorder characterized by myoclonia that is often the first symptom followed by generalized epilepsy, ataxia, weakness and dementia. The onset normally manifests in childhood, after normal early development. The clinical diagnosis of MERRF is based on the following four “canonical” traits: myoclonus, generalized epilepsy, ataxia and red-ripped fibers (RRF) in muscle biopsy. A 23-year-old female patient who began her illness at 19 years of age, previously healthy, first with generalized tonic-clonic seizures that were difficult to control initially, since she currently had 2 medications; the following year he has generalized weakness, ataxic gait, weight gain, dysarthria and prostration in a wheelchair, with progressive and irreversible deterioration. Muscle biopsy is performed demonstrating red fibers torn through the Gomori trichrome technique. The electrocardiogram is normal.

 

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Depression from Sadness to Melancolia - ANN

Sometimes  we  have  felt  so  sad  and  so  disappointed  for  a  few  hours  or  days,  situation  that  leads  us  to  sleep  badly,  have  awakenings   consists   before,   decreased   appetite,   easy   crying,   tiredness, attention deficit, grumpy, even wanting to “swallow the Earth” which is a small thought to “want to die”; These situations are normIn the mood swings we experience throughout the L day or in
a few weeks, and that is recovering with the passage of time, thanks to the adjustment in your brain neurotransmitters experience, we have already commented that they are chemicals in the brain that allow to carry out the different phases of thought.

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How the Musicality of Ethnolinguistic Affects the Cognitive Abilities for Further Learning - ANN

The Albanian native speaker’s have  a better pronunciation or accent of the foreign language they learn and these phenomena are unique in so called Indo-European languages group, a family group where  Albanian  is  one  of  the  oldest  surviving  member.  Albanian  language  richness  in  sound  is  expressed  with  writing  system    of  different  large  alphabets  up  to  53  letters.  Further  certain  element  of  ethnography  of  singing  such  as  iso-polyphony  considered  by  UNESCO  as word heritage which has been a form of ancient singing in north as well in the south Albania including Macedonia still vivid in  Albania.  Characterized  by  songs  consisting  of  two  solo  parts,  a  melody and a countermelody with a choral drone. 

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Perception of Over the Counter Drug Advertising among Pharmacists in Abu Dhabi, UAE - APPR

Over-The-Counter  drugs  (also  called  OTC  or  non-prescription  drugs)  are  the  most  important  self-medication  means  used  in  the  treatment of health problems and are defined as drugs that are safe, effective and available at pharmacies without doctor’s prescription [1,2]. The change of drug status from prescription only medicine to  OTC  brings  advantages  to  patients,  general  practitioners, pharmacists,  pharmaceutical  companies  and  the  government. Patients can benefit from more effective treatment being readily available  to  treat  a  wide  range  of  minor  ailments  without  the  need  to  see  their  doctors. 

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Level of Micronutrient [Zinc] and its Association with Seizures in Children: A Case Control Study - APPR

Brain  consists  of  nerve  cells  that  usually  communicate  with  each other through electrical activity thus, controls and regulates all voluntary and involuntary responses in the body. When region(s) of brain receives a burst of abnormal electrical signals that temporarily interrupts   normal   electrical   brain   function   a   seizure   occurs.   Transient  occurrence  of  signs  and  or  symptoms  resulting  from  abnormal excessive or synchronous neuronal activity in the brain is defined as seizure. Febrile seizures are defined as the seizure that occurs  between  the  age  of  6  and  60  months  with  a  temperature  of  38  °C  or  higher  that  are  not  the  result  of  CNS  infections  or  any  metabolic imbalance, and that occur in the absence of a history of prior afebrile seizures.

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Adjustable Quarto Stimuli (T, pH, Redox, Hyperthermia) Targeted Nanocontainers (Nano4Dox and Nano4Cis) for Cancer Therapy Based on Trojan Horse Approach - APPR

We developed a quadrupole stimuli responsive targeted nanomedicine platform with the key goal to provide a solution to the outstanding  problem  “How  can  the  delivered  therapeutic  dose  to  the  tumour  be  increased  while  at  the  same  time  reducing  the  dose in healthy tissue?” When accomplishing this goal, we will offer a huge improvement in the length and quality of life of cancer
patients. Our preliminary animal study give hope in that course. We attempted to accomplish this goal via an innovative and patented therapeutic approach based on novel polymeric nanocarriers (NCs), which enables targeted drug delivery in tumors. The in-vivo results suggest that both Nano4Dox and Nano4Cis platforms outperforms the commercial standards like Doxil® and Lipoplatin, respectively. These platforms offer a significant business opportunity besides the therapeutic value offering to millions of people hope for better life and cure.

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Lattice Boltzmann Method Computation of Turbulent High-Temperature Plasma Jets - Engineering Sciences

This paper aims, firstly, to provide an investigation of plasma jets dynamics by the help of the Lattice Boltzmann method (LBM) and second to test the computational efficiency of the LB method by comparison of its results to former measurements and numerical findings. The plasma gas is the argon injected at 520 m/s and 13500 K. In this study we accounted for highly variable thermophysical
properties dependence on temperature. The LB results using the proposed model seems to give an excellent compromise between former  experimental  and  numerical  results  using  classical  methods  (FDM,  FVM),  while  the  deviations  were  found  with  other  simulations attempts by the LB method. 

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Interactive Big Data Analytics Platform for Healthcare and Clinical Services - Engineering Sciences

A Big Data Platform (BDA) with Hadoop/MapReduce technologies distributed over HBase (key-value NoSQL database storage) and generate hospitalization metadata was established for testing functionality and performance. Performance tests retrieved results from simulated patient records with Apache tools in Hadoop’s ecosystem. At optimized iteration, Hadoop distributed file system (HDFS) ingestion with HBase exhibited sustained database integrity over hundreds of iterations; however, to complete its bulk loading via MapReduce to HBase required a month. The framework over generated HBase data files took a week and a month for one billion (10TB) and three billion (30TB), respectively. Apache Spark and Apache Drill showed high performance. However, inconsistencies of Map Reduce limited the capacity to generate data. Hospital system based on a patient encounter-centric database was very difficult to establish because data profiles have complex relationships. Recommendations for key-value storage should be considered for healthcare when analyzing large volumes of data over simplified clinical event models.

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Demystifying Role of Ultrasound Elastography in the Evaluation of Primary Open Angle Glaucoma WJOVR- Iris Publishers

Glaucoma  is  the  one  of  the  most  common  cause  of  blindness  worldwide [1,2]. Though glaucoma’s pathogenesis remains poorly understood, it is known to inflict damage upon the optic nerve head (ONH), the severity of which increases with increased intraocular pressure  (IOP)  [3,4].  Playing  a  central  role  in  ONH  biomechanics,  the  sclera-the  eye’s  stiffest  tissue-constitutes  more  than  70%  of  the outer envelope of the bulbus oculi [5]. Scleral stiffness [6] and scleral collagen fiber organization [7] correlate with IOP-induced deformation of the ONH. Scleral stiffness in particular also changes with age [8] and chronic IOP elevation [9].

https://irispublishers.com/wjovr/pdf/WJOVR.MS.ID.000501.pdf

Bacterial and Fungal Oral Infections Among Patients Attending Dental Clinics in Sana’a City-Yemen OJDOH - Iris Publishers

The aims of this study were to determine the frequency of clinical diagnosis of oral infections and to identify the bacterial and fungal causative agents and their frequency in patients attended the dental clinics at Al-Gumhouri Teaching Hospital in Sana’a city-Yemen.The study carried out for one year, starting in December 2011 and ending in November 2012. The study included 296 patients of whom 153 were males and 143 were females, their ages ranged from 5 to 65 years old, with a mean age of 36.2 years. Clinical and demographic data were collected in standard questionnaire then oral swabs or pus were collected from patients and cultured, isolated and identified using standard laboratory techniques.The prevalence of different clinical oral infections were 20.6% for dental abscesses, 19.3% for periodontal abscesses, 17.6% for gingivitis, 16.6% for periodentitis, 10.1% for dental caries, 8.4% for pulpitis and 7.4% for oral thrush. Out of the total 296 cultured swabs, only 217 swabs yielded positive culture with a percentage of 73.3%. Gram-Positive bacteria constituted 67.4% of the total isolates, where Staph. aureuswas the predominant pathogen (43.1%), whereas, the Gram-Negative bacteria represented only 26.6% of the total isolates, in which Bacteroides spp was the predominant Gram-Negative isolate (26.6%), and finally Candida  albicans constituted only 6% of the total micro-organisms.

https://irispublishers.com/ojdoh/pdf/OJDOH.MS.ID.000504.pdf

Use of Endodontic Cores for Rigid Screw Retention of the Natural Dentition to Dental Implants by Means of Fixed Partial Prostheses for the Atrophic Mandible: Long-Term Clinical Results OJDOH - Iris Publishers

Implant-supported  prostheses  have  been  first  choice  for treating lost teeth. However, there are challenging cases that only reach resolution by exploring unconventional options. In order to  overcome  specific  shortcomings,  tooth-implant  supported prostheses  have  shown  to  be  a  predictable  treatment  option. The  most  significant  difference  between  an  implant-supported prosthesis, when compared to a tooth-supported, is the absence of a periodontal ligament (PDL). This anatomic structure is responsible for tooth movement, shock absorption, and proprioception [1-3].

https://irispublishers.com/ojdoh/pdf/OJDOH.MS.ID.000502.pdf

Oral Microbiome and Response to Immunotherapy: Is It Time To Pay Attention? OJDOH - Iris Publishers

Microbiome studies have shown associations between the presence of certain bacteria in the gut and response to checkpoint inhibition (CPI) therapies in cancer patients. Studies looking at any such potential associations between oral microbiome and response to CPI therapies are lacking. Oral cavity is an important microbial habitat. Microbes present in the oral cavity influence not only the local and systemic immune homeostasis; but also the gastrointestinal microbial diversity. If associations exist between specific gut microbes and response to CPI therapies, it is reasonable to assume that such relationships exist between oral microbes and therapy response in cancer patients. Since the findings from such studies will have resounding implications on patient selection for therapies and prophylactic or therapeutic modulation of microbes for prevention or treatment of malignancies; it is crucial that dental and oral research community pays attention and joins this research effort to identify associations and elucidate mechanisms of oral microbial determinants of CPI therapy responses in cancer patients.

https://irispublishers.com/ojdoh/pdf/OJDOH.MS.ID.000501.pdf

Antibiotic Resistance and Upper Respiratory Infections OJOR - Iris Publishers

Resistance to antibiotics are part of the threats to global health today,  resistance  can  affect  anyone  in  the  world  who  is  facing  an  infectious  process  of  any  kind.  This  phenomenon  is  a  natural  process, in any living being that seeks to maintain itself, reproduce and  perpetuate  itself,  although  the  improper  use  of  antibiotics  is  accelerating the process.

https://irispublishers.com/ojor/pdf/OJOR.MS.ID.000502.pdf

Quality of Life in Pediatric Patients with Serous Otitis Media using the OM6 Questionnaire, Centro Médico Nacional Del Noroeste, Instituto Mexicano Del Seguro Social Sonora, México OJOR - Iris Publishers

Serous otitis media is simply the accumulation of fluid in the  middle  ear  without  signs  and  symptoms  of  ear  infection.  Asymptomatic serous otitis media can be classified as acute (less than 3 weeks), subacute (3 weeks to 3 months) or chronic (more than 3 months). The term acute or chronic refers to the time course of the disease, not the severity [1]. 

https://irispublishers.com/ojor/pdf/OJOR.MS.ID.000501.pdf

Review on Organ Preserving Techniques in Patients with Urethral Carcinoma AUN - Iris Publishers

Tumors of the urethra are rare and often require radical surgery when dealing with locally advanced tumors to achieve adequate local  control  of  the  disease.  In  males,  these  procedures  include  partial  or  total  penectomy  for  distal  urethral  carcinoma  or  total  penectomy with cyst prostatectomy for proximal urethral carcinoma. In females with locally advanced urethral carcinoma, anterior exenteration may be required for better oncological outcomes. Patients diagnosed with urethral carcinoma at earlier stage may be amenable for genital sparing surgery which offers preservation of body image and better quality of life. We sought to review the current  available  literature  describing  different  techniques  of  surgical  management  in  patients  with  primary  urethral  carcinoma  and subsequent survival and oncological outcomes.

https://irispublishers.com/aun/pdf/AUN.MS.ID.000501.pdf

Addiction to Tobacco: A War That Begins to Win OAJAP - Iris Publishers

For several centuries humanity has become addicted to tobacco, as a social entrance to an allowed addiction, and that each smoker was charged its respective bill, with ways to die of the most brutal and suffered possible.The complications of nicotine addiction are based on the form of  its  entry  route,  which  is  respiratory  due  to  smoking,  and  hence  the  complications  of  the  referred  habit,  mainly  emphysema  and  lung cancer.

https://irispublishers.com/oajap/pdf/OAJAP.MS.ID.000502.pdf

Meaningful Learning Effectiveness Related to Nets Codes in Students with Autism Spectrum Disorder OAJAP - Iris Publishers 

One of the characteristics of students with Autism Spectrum Disorder (ASD) is significant deficits in coding global learning. Simmons  Barsalou  [1]  propose  a  cognitive  structure  corresponding  to  different  subsystems  configured  by  interconnected conceptual  phases,  which  people  with  ASD  are  important  delays  in  semantic  processing.  From  Vigostkian  perspective,  students  assimilate  all  the  concepts  that  make  sense  and  are  meaningful  them,  so  this  research  main  aim  is  to  investigate  effectiveness  of  creating meaningful relationships between concepts to improve learning integrated into curriculum in people with ASD. There ́s few evaluation studies of this theoretical principles integration into curriculum, so this research ́s main aim ́s to investigate effectiveness of creating meaningful relationships.

https://irispublishers.com/oajap/pdf/OAJAP.MS.ID.000501.pdf

The Interleukin-1β (-511T/C) is Associated with Ulcerative Colitis SJGH - Iris Publishers

Inflammatory bowel disease (IBD) is a group of illnesses whose primary manifestation is inflammation. The most common typical phenotypes are ulcerative colitis (UC) and Crohn’s disease (CD). Although the precise etiology remains obscure, several reports have indicated that dysfunction of the mucosal immune system play an important role in its pathogenesis. This study aimed to analyzing the genes polymorphisms of immune response in Brazilian patients with IBD. 

https://irispublishers.com/sjgh/pdf/SJGH.MS.ID.000502.pdf

Iris Publishers- Open access journal of Gastroenterology & Hepatology| Understanding the Integrated Gene Regulatory Networks for Hepatocellular Carcinoma

Hepatic cancer is a malignant tumor that begins in the cells of the liver. The leading cause is a viral infection with hepatitis B and hepatitis C. Hepatocellular carcinoma (HCC) has become the most common form of hepatic cancer. It is the fastest-growing cause of cancer deaths in the United States. HCC is also found to be associated with obesity, type 2 diabetes and fatty liver disease. To understand the gene expression regulation during HCC development, scientists have identified a few related transcription factors (TFs) and characterize their roles such as E2F1[1], Foxm1b [2] and hepatic nuclear factors [3]. However, these findings still cannot fully explain the underlying molecular mechanism during liver tumorigenesis. It is necessary to systematically study the global gene regulatory network (GRN) during HCC development.
The advancement of next-generation sequencing (NGS) technologies has enabled the rapid examination of the entire human genome. Many NGS applications have been developed to profile cells such as RNA-seq [4], ChIP-seq [5], ATAC-seq [6] etc. These allow scientists to study cells at different levels including genome, transcriptome, and epigenome. For instance, ChIP-seq and ATAC-seq data can be used to learn the chromatin states of certain biological processes by detecting regulatory elements in the genome and corresponding transcriptional regulators. Furthermore, recent developments in high-throughput single-cell technology provide the statistical power to study diverse population of tumor cells. This can greatly help scientists to understand intratumoral heterogeneity.

To read more...Open access Journals of Gastroenterology 

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The Ultimate Game Against Nature GJNFS - Iris Publishers

Economist N. Stern has played a majpe in the scientic debate about global warming. Thus, in 2007 he raised correctly the issue about  the  biggest  even  externality  in  the  history  of  human  societies.Thaw  emission  of  GHGs  were  seen  by  Stern  as  an  example  of market failure, having very serious negative effects upon all countries. In 2015, he asked” What are we waiting for?”, believing perhaps  somewhat  naively  that  external  effects  could  internalized  between  the  countries  as  easily  as  externalities  are  corrected  within a county. Policy-making and implementation on climate change is very difficult and complicated, because of the PD at the core of global warming.

https://irispublishers.com/abba/pdf/ABBA.MS.ID.000502.pdf

Biomathematical Analysis of the Liver Fibrosis ABBA - Iris Publishers

Liver fibrosis is the final common stage of the most chronic liver diseases, it is caused by several factors which lead to a major worldwide health care burden. Over the decades, the understanding of the liver fibrosis disease was growing rapidly, several studies reported that this progress could be regressed or reversed, which give us a bright prospect in developing anti-fibrotic therapies.In this experiment, liver fibrosis was fully developed after CCl4induction for 7 weeks in eight animals. Clinical pathologic parameters, four indicators of hepatic fibrosis in monkey showed similarly changes in human. All animals had liver fibrosis after 1.5 months of CCl4 induction, and liver fibrosis still existed after 9 months recovery periods, the fibrosis stages in most animals had no obvious regression without treatment. Biomathematical analysis of the liver fibrosis would aid to utilize the anti-fibrotic therapies and their derivatives for various biomedical applications.

https://irispublishers.com/abba/pdf/ABBA.MS.ID.000501.pdf

Protein for Sports Persons and Myths about Plant-Based Protein GJNFS - Iris Publishers

Any of a class of nitrogenous organic compounds  which  have  large  molecules composed of  one  or more long chains of amino acids and are an essential part of all living organisms, especially as structural components of body tissues such as muscle, hair, etc. and as enzymes and antibodies.

https://irispublishers.com/gjnfs/pdf/GJNFS.MS.ID.000507.pdf

Maternal Knowledge on Complementary Feeding Practice and Nutritional Status of Children 6-23 Month in Jigjiga Town GJNFS - Iris Publishers

The  purpose  of  this  study  was  to  determine  mothers  knowledge  on  complementary  feeding  practices  and  relate  this  to  the  nutritional status of their children aged 6-23 months. The study adopted a cross-sectional analytical study design and was carried out  at  the  kebele  05  in  Jigjiga  town  among  the  randomly  sampled  110  mothers  and  their  children.  A  researcher-administered  questionnaire was used to collect data. Data was entered and analyzed using SPSS version 20 ENA [1]. Anthropometric measurements were analyzed using Microsoft Excel. The respondents were mostly young (mean age 27.7±4.7 years), married (87.3%), housewives (70%)  with  mainly  primary  school  level  of  education  (48.2%).  The  main  sources  of  income  for  most  households  were  business  (48.6%) and casual labor (31.8%). Mothers had high knowledge on complementary feeding practice (90%) out of the 20 knowledge questions.  All  (100%)  the  children  aged  6-8  had  been  introduced  to  solids,  semi-solids  and  soft  foods.  Majority  of  the  breast-fed  children  received  minimum  meal  frequency  were  6-8  months  old  (86.7%)  and  9-23  months  old  (90%)  unlike  the  non-breast  fed  children  (80%).  Overall,  52.7%  of  all  the  children  were  stunted,  49.1%  wasted  and  43.6%  underweight.  Maternal  knowledge  on  complementary feeding was significantly associated with nutritional status of their children. Mothers knowledge on feeding the sick and recovering children was related to underweight in children. The same was true of mothers who knew that a child’s main meal should be diversified. Mothers knowledge on complementary feeding practices was not significantly related to her complementary feeding practices (p>0.05). Nutrition programme should pay attention to cultural beliefs on infant and young child feeding.

https://irispublishers.com/gjnfs/pdf/GJNFS.MS.ID.000506.pdf

Diet and Nutrition: Metabolic Diseases GJNFS - Iris Publishers

“You Are What You Eat; how to win and keep health with diet”, was the title of a book, that nutritionist Victor Lindlahr wrote in 1920s. Since then, several nutritionists have written extensively on this topic. Over the years, scientists, clinicians, policy makers, and professional societies, have offered contradictory advice of what to eat or what not to eat, and when to eat. In view of the fact,
that my interests are focused on metabolic diseases, I will start this essay with some introduction to metabolism, as it modulates the activities at molecular, cellular, organ, and total body level. In brief, metabolism is the chemical process your body uses, to transform the food you eat into the fuel, that keeps you alive and well. Diet and nutrition by and large, consists of proteins, carbohydrates, fats
and a variety of micronutrients. These substance’s when ingested are broken down by enzymes in our digestive system, and then carried to the cells, where they can be used as fuel. The body either uses these metabolites immediately, or stores them in the liver, body fat, and muscles for later use. A metabolic disorder occurs, when the metabolic process fails and causes body to have either too much or too little of the essential metabolites needed to stay healthy. In the ancient science of Ayurveda, the Indian Traditional Medicine, alterations in metabolism are called “doshas”, meaning metabolic defects. In the holistic approach, attempts are made to keep these dos has in a perfect balance, so that the risks for various diseases are not developed. All the known metabolic diseases, such as hypertension, excess weight, endothelial dysfunction, subclinical atherosclerosis, obesity, metabolic syndrome, and type-2 diabetes, have reached epidemic proportions worldwide. In this overview, we will discuss some of the known metabolic alterations that promote the risks for developing metabolic diseases and present our views on the subject.

https://irispublishers.com/gjnfs/pdf/GJNFS.MS.ID.000505.pdf

The Public Function in The Regulation of Food: Ethics and Prevention GJNFS - Iris Publishers

The restriction of transgenic components of high toxicity, the use of contaminated irrigation water with poisonous pesticides, as well the indiscriminate comestible animals fed with synthetic hormones, should be prohibited and sanctioned by the sanitary authorities under a World Health Council of Public Health, regulated by a group of international observers, not financed by the private  food  industry,  either  by  transnational  linked  to  the  edible  industry,  with  authority  to sanction  irregularities  and  compel  government media campaign disclosure to the population on consumption risks.

https://irispublishers.com/gjnfs/pdf/GJNFS.MS.ID.000504.pdf

Acupuncture GJNFS - Iris Publishers

Acupuncture  involves  the  activation  of  specific  points  of the  skin,  usually  by  inserting  needles.  Acupuncture  was  based  on   the   principles   of   Chinese   traditional   medicine.   Traditional   acupuncturists  perceived  health  in  terms  of  a  violent  force  or  energy, called Qi, which circulates between organs along channels that are called meridians. The flow of energy “Qi” must have the right  strength  and  quality  in  each  of  these  meridians  and  organs,  so  as  to  maintain  health. 

https://irispublishers.com/gjnfs/pdf/GJNFS.MS.ID.000503.pdf

A Toxicological Investigations in Food GJNFS - Iris Publishers

Since its inception, Global Journal of Nutrition & Food Science is  going  to  publish  reports  which  provides  more  coherent  and  varied  viewpoints  on  such  subjects,  the  journal  is  introducing  a  new  feature  under  our  editorship.  Beginning  with  this  issue  and  periodically  hereafter,  the  journal  will  present  an  evaluation  or  planning  case  study  along with  critiques  by  relevant  researchers  or practitioners.

https://irispublishers.com/gjnfs/pdf/GJNFS.MS.ID.000501.pdf