Demystifying Role of Ultrasound Elastography in the Evaluation of Primary Open Angle Glaucoma WJOVR- Iris Publishers

Glaucoma  is  the  one  of  the  most  common  cause  of  blindness  worldwide [1,2]. Though glaucoma’s pathogenesis remains poorly understood, it is known to inflict damage upon the optic nerve head (ONH), the severity of which increases with increased intraocular pressure  (IOP)  [3,4].  Playing  a  central  role  in  ONH  biomechanics,  the  sclera-the  eye’s  stiffest  tissue-constitutes  more  than  70%  of  the outer envelope of the bulbus oculi [5]. Scleral stiffness [6] and scleral collagen fiber organization [7] correlate with IOP-induced deformation of the ONH. Scleral stiffness in particular also changes with age [8] and chronic IOP elevation [9].

https://irispublishers.com/wjovr/pdf/WJOVR.MS.ID.000501.pdf