Iris Publishers- Archives of Clinical Case Studies | Epidermal Cyst of the Plantar Foot
Authored by Charles B Parks
Epidermal inclusion cysts are benign lesions that are rarely seen on the foot due to its lack of sebaceous glands. (Paparelli) We report a case of a 70-year-old male with an inclusion cyst for over 5 years. Radiographs and magnetic resonance imaging revealed the presence of subcutaneous mass with a growing epidermoid.Epidermal inclusion cysts (also commonly referred to as epidermal cysts, epidermoid cysts and infundibular cysts) are benign cysts in the epidermal region of the skin. Comprising about 85-90% of all excised subcutaneous cysts, they are relatively common. (Kim, Nigam) The cyst is most often found in the hair bearing surfaces of the body due to a displacement and proliferation of the epidermal cells within the dermis, or from inflammation of the pilosebaceous glands. A 41 years old Moroccan woman with a 6-year history of GPP was admitted with an acute, severe flare of pustulation. On exanimation, she was febrile and had disseminated, painful pustules primarily over the back, the upper and lower extremities (Figure 1A). There was a generalized erythema covering approximately 80% of the body surface area; the dermatology life quality index (DLQI) was 21. Secukinumab 300 mg with initial dosing at weeks 0, 1, 2 and 3, followed by monthly maintenance dosing starting at week 4 was administered in association with acitretin 0.4 mg/Kg/day. Within 2 weeks after the first secukinumab dose, there was an improvement in her general state, partial resolution of pustules and erythema. Complete GPP clearance was achieved at month-2 (Figure 1B) when DLQI score was 4. The patient was otherwise healthy, and she was taking hormonal contraception. The beneficial was maintained during the 14 months of follow up.
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Epidermal inclusion cysts are benign lesions that are rarely seen on the foot due to its lack of sebaceous glands. (Paparelli) We report a case of a 70-year-old male with an inclusion cyst for over 5 years. Radiographs and magnetic resonance imaging revealed the presence of subcutaneous mass with a growing epidermoid.Epidermal inclusion cysts (also commonly referred to as epidermal cysts, epidermoid cysts and infundibular cysts) are benign cysts in the epidermal region of the skin. Comprising about 85-90% of all excised subcutaneous cysts, they are relatively common. (Kim, Nigam) The cyst is most often found in the hair bearing surfaces of the body due to a displacement and proliferation of the epidermal cells within the dermis, or from inflammation of the pilosebaceous glands. A 41 years old Moroccan woman with a 6-year history of GPP was admitted with an acute, severe flare of pustulation. On exanimation, she was febrile and had disseminated, painful pustules primarily over the back, the upper and lower extremities (Figure 1A). There was a generalized erythema covering approximately 80% of the body surface area; the dermatology life quality index (DLQI) was 21. Secukinumab 300 mg with initial dosing at weeks 0, 1, 2 and 3, followed by monthly maintenance dosing starting at week 4 was administered in association with acitretin 0.4 mg/Kg/day. Within 2 weeks after the first secukinumab dose, there was an improvement in her general state, partial resolution of pustules and erythema. Complete GPP clearance was achieved at month-2 (Figure 1B) when DLQI score was 4. The patient was otherwise healthy, and she was taking hormonal contraception. The beneficial was maintained during the 14 months of follow up.
To read more... Clinical case Studies
To view more journals... Iris Publishers
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