Friday, March 29, 2019

Iris Publishers- Open access Journal of Clinical Case Studies | The Human Heart Electrophysiological Data Visualization: A Review


Authored by Lei Zhang

By the comprehensive mathematical description of cardiac biochemistry, bioelectricity and biophysics, cardiac computational models simulate function and behavior of the heart so that researchers can understand the underlying mechanism of cardiac activity. So, visualize the electrophysiological data is of great importance. In this paper, we review the progress for the development of the visualization method of the human heart electrophysiological data. Cardiac electrical activities are valuable for the investigation of complex heart diseases, e.g., arrhythmias, ischemia, and ventricular fibrillation, and can be invasively measured by medical devices like electrocardiogram (ECG). With the progress in programmed electrical modeling and simulation, electrophysiological simulation has gradually been a promising direction and an essential method for cardiac electrophysiology study to understand the mechanism and functionality of the heart. By simulating the cardiac electrical activities over a wide variety of scales from single ion channel proteins to whole organs, cardiac electrophysiological simulation can help in revealing the mechanisms of normal and abnormal cardiac electrical activities, interpreting of clinical data, and even designing drugs and therapeutic plans. Due to the complex structure of the heart, the large amount of data and the hidden electrophysiological feature, to observe the electrophysiological is a challenging task. Fortunately, researchers have been dedicated to propose visualization method to facilitate the research of electrophysiological simulation.


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