Authored by Juana Hutchinson-Colas*
Abstract
Benign Gynecologic surgery for the elderly patient has certain considerations for the provider to be aware of. As the population ages, more women require benign gynecologic procedures. To date, there are no guidelines regarding pre-operative, intra-operative, and post-operative care specific to this patient population. This outline provides a reference for providers when approaching the elderly patient in need of benign gynecologic surgery.
Introduction
The need for surgical treatment of benign gynecological conditions will increase as women are living longer and the incidence of pelvic floor disorders increase with aging. Pelvic floor disorders such as prolapse and urinary incontinence cause significant physical and emotional distress and sometimes require surgical management.
When preparing a patient for benign gynecologic surgery, there are certain chronic health issues to consider. For all patients, one must take into account the overall health of the patient, preoperative workup, surgery itself, and post-operative recovery. In the elderly patient, there are additional considerations to keep in mind. For many reasons including patient safety, the elderly should not be grouped into the same category as a younger, healthier patient when preparing for surgery. To date, there are no universal guidelines to assist the provider in preparing the elderly patient for benign gyn surgery. This paper outlines the pre-operative, intraoperative, and post-operative practices to optimize this surgical care.
The most common conditions for benign gynecologic surgery in the elderly population include post-menopausal bleeding, pelvic organ prolapse, urinary incontinence, and benign tumours such as persistent ovarian cysts. Surgical treatment for the above conditions include dilation and curettage, diagnostic and operative laparoscopy, vaginal and abdominal hysterectomy, laparoscopic hysterectomy, uterine/vaginal suspension procedures, vaginal obliteration, and mid-urethral retro pubic or trans-obturator slings. Most of these procedures are minimally invasive in nature or can be performed by minimally invasive techniques. According to the American College of Obstetrics and Gynaecologists (ACOG), when feasible a vaginal approach is the preferred route for hysterectomy since there are demonstrated improved patient outcomes, shorter operative time, and faster recovery. Also, vaginal approach allows for various anaesthesia techniques including regional, which is beneficial for the elderly patient. When vaginal approach cannot be achieved, laparoscopy should be considered. Both of these minimally invasive techniques are preferred over abdominal approach in the elderly population [1].
Pre-Operative
The pre-operative workup of an elderly patient undergoing benign gynecologic surgery should follow certain guidelines. As in all medical conditions, the most important first step is a thorough history and physical. Knowing the elderly patient’s medical history provides important information to be able to optimize her for elective surgery and minimize potential complications. The history of present illness, past medical and surgical history is primary areas of focus as we begin her workup.
The history of present illness lets the patient tell her story in her own words. It is essential to elicit the most bothersome symptoms since many benign gynecologic interventions in the elderly population are driven by the patient’s discomfort. Personal or familial history of thrombo-embolic events is important to consider so that deep venous thrombo-embolic prophylaxis can be offered. One important aspect of the history is the social history because many elderly depend on their family or health care proxy for immediate post op care and recovery assistance. This can identify any areas that need to be addressed before surgery, such as, social services, visiting nurses and rehabilitation facilities.
When performing a physical examination on the elderly patient, there are certain areas on which to focus. First, we note the general ambulation and nutritional status of a patient. For example, can she walk from the waiting room into the examination room? Does she need assistance with a walker or wheelchair? These initial observations give us a useful overview of the general health and performance status. The physical exam continues with a cardiopulmonary exam including heart, lung, and pulses. Next, joint mobility is determined as this may be limited in the elderly patient with history of arthritis. Joint mobility and limitation are important considerations during patient positioning in the operating room. Many gyn procedure are performed in dorsal lithotomy where hip and knee mobility, or lack thereof, can affect successful set up and surgery. Patients may need to be positioned in dorsal lithotomy prior to anesthesia induction to maximize patient comfort and safety. Throughout the history and physical examination, the neurologic status of the patient can be determined. If there is a question of the patient’s neurologic status, the mini-mental state examination, a 30-point questionnaire assessing cognitive function, can be employed. This may be helpful in determining capacity and ability of patient to fully understand informed consent.
Cardiovascular risk calculators
According to the most recent Centres for Disease Control and Prevention (CDC) guidelines, heart disease is the leading cause of death in women of all races and origins in the United States [2]. Therefore, when preoperatively evaluating the elderly gyn patient for surgery, cardiovascular risk assessment is essential. There is several cardiovascular risk calculators used preoperatively to predict certain cardiac events.
The revised cardiac risk index (RCRI) by Lee et al. has been validated and used for over 20 years to assess preoperative cardiac risk. The RCRI takes into account the patient’s history, current medical health condition, and type of surgery to stratify patient’s risk for a cardiac complication during a non-cardiac surgery. This tool provides the health care provider with the risk of a cardiac complication and can assess the need for further cardiac testing, but it does not identify non-cardiac risks for patients [3]. Another method is the National Surgical Quality Improvement Program (NSQIP) risk prediction calculator, which has been validated in over 1.5 million patients. This web-based decision-support tool estimates risk to patient and has proven accuracy in predicting morbidity and mortality [4]. Based on one of the above risk calculators, a provider will obtain a risk of cardiovascular event for a patient. If the risk is <1%, the patient is considered to be low risk and no further cardiac workup is needed. If the risk score is >1%, then the patient is considered higher risk and further testing may be necessary.
High risk cardiac patients should be considered for further cardiovascular evaluation. The 2014 American College of Cardiology/American Heart Association (ACC/AHA) is an important guide to determine the functional status of a patient. If she is able to complete four or greater metabolic equivalents (METS) without symptoms, no further cardiac testing is needed. For example, if she can climb one flight of stairs without shortness of breath, she may not need a comprehensive cardiac workup. If she is unable to do so, additional testing should be ordered [5].
Diabetes
In the elderly population, diabetes is a common condition that should be addressed since perioperative hyperglycaemia poses a significant infection risk and can delay wound healing. Elective surgery should only be performed when the patient’s HgbA1C is below 7 as this has been proven to decrease postoperative wound infection [6]. In addition, patients with a history of diabetes are also at increased risk of coronary heart disease, hypertension, obesity, all which increase perioperative risk. Early surgical start time (before 9AM) may present an additional advantage to the diabetic patient and minimizes disruption of management of glucose control.
Medications
A complete review of all medications both prescribed and over the counter is important. Some medications should be discontinued weeks before surgery, while others should be continued until the morning of the procedure. For patients with hypertension, beta, alpha and calcium channel blockers should be continued as prescribed and taken the morning of surgery with a sip of water. In particular, stopping beta blockers prior to surgery has proven to increase cardiac morbidity and mortality [7-9]. Because of the risk of rebound hypertension with acute cessation of alpha-2 blockers such as clonidine, these medications should also be continued pre-operatively. Continuing calcium channel blockers during perioperative period has no proven contraindications.
Angiotensin-converting enzyme (ACE) inhibitors and angiotensive-2 receptor blockers (ARBs) are common antihypertensive that should be used with caution preoperatively. Patients taking either ACE inhibitor or ARB in combination with a diuretic are at risk for intraoperative hypotension [10]. Therefore, these medications should not be taken the morning of surgery. ACE inhibitors, ARBs, and diuretics may be resumed within 48 hours postoperatively. Patients taking statins should continue this therapy. In fact, in one international prospective cohort study, the use of statins in patients undergoing non-cardiac surgery was associated with a lower risk of cardiovascular outcomes 30 days after surgery [11]. However, no studies exist that suggest starting routine statin use in a patient not already using this medication.
Women who are taking hormone replacement therapy (HRT) are encouraged to stop prior to surgery. HRT increases the risk of venous thromboembolism (VTE), and since surgery alone also increases this risk, the compounded effect of HRT in a surgical patient should be avoided [12]. Many women on HRT are perimenopausal or at the start of menopause. The elderly patient population is usually not on HRT, so this becomes less of a consideration. On the other hand, selective estrogen receptor modulators (SERM) may more commonly be used in the elderly gynecologic population in treatment of breast cancer (tamoxifen) or osteoporosis (raloxifene). SERMs increase the risk of VTE and care must be taken prior to surgery. Raloxifene should be stopped 3 days prior to surgery. Tamoxifen as a breast cancer prevention strategy should be stopped 2 weeks prior to surgery. However, when tamoxifen is being used for breast cancer treatment, one can consider continuation of the drug with additional measures for VTE prophylaxis [13].
Prevention VTE
All surgical patients are risk stratified for risk of VTE. The American College of Chest Physicians Caprini score is universally used as a preoperative assessment tool for VTE during surgery and guides intra-operative prevention. Women aged 61-74 years old receive 2 points on the risk score model, while women aged 75 years and older receive 3 points. Other points that apply to the elderly gyn population include cancer, prior VTE, estrogen use, smoking, and obesity. Low risk patients (Caprini score 1-2) have 1.5% estimated baseline risk of VTE should have mechanical prophylaxis during surgery. Moderate risk patients (Caprini score 3-4) should have intermittent pneumatic compression device applied and can be considered for chemical prophylaxis with low molecular weight heparin or low dose unfractionated heparin if they do not have a bleeding risk. Finally, high risk patients (Caprini score greater than or equal to 5) have a 6% estimated baseline risk of VTE and should receive chemical VTE prophylaxis intraoperative in addition to mechanical prophylaxis [14].
Informed consent
Informed consent begins with a discussion regarding the nature of the patient’s problem and degree of bother. It continues with reviewing treatment options and desired outcomes. Once preoperative assessment is completed, a surgeon is better able to provide the patient with specific benefits and risks of various treatment options. Having a family member present for preoperative consent can be helpful for the patient in recalling the discussion and the salient points critical to informed consent. Also, the pre-operative visit can be an overwhelming experience for any patient. Being accompanied by a trusted confident, family member or friend may alleviate some anxiety while providing a personal witness to the conversation. We encourage having a family member or care provider present because they will also be involved in perioperative instructions and post-op care.
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