Simultaneous Monitoring of Intracranial Pressure and Cerebral Blood Flow in Patients with Severe Brain Injury - Neurology & Neuroscience

 

37 patients with severe brain injury (admission Glasgow Coma Score 8 or below) were simultaneously monitored for intracranial and cerebral perfusion pressure and cerebral blood flow using transcranial Doppler ultrasonography. Pearson correlation coefficients were calculated to analyze relationships between quantitative variables. It was established that the increase of intracranial pressure leads to formation of Doppler ultrasonographic pattern of reduced perfusion, which involves relative decrease of mean linear blood flow velocity (primarily due to decrease of end-diastolic blood flow velocity) and increase of peripheral resistivity indices (pulsatility and resistivity indices).

 

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